Latar Belakang: COVID-19 merupakan pandemi yang telah mengakibatkan tingginya angka mortalitas di berbagai belahan dunia. Pengetahuan mengenai pandemi COVID-19 penting untuk diketahui oleh seluruh kalangan masyarakat terutama pada kelompok lanjut usia (lansia. Pentingya lansia memiliki pengetahuan dan kepatuhan mengenai COVID-19 dan menjaga protokol kesehatan yakni memakai masker, mencuci tangan, dan menjaga jarak dan disingkat dengan istilah 3M.
Tujuan: untuk mengetahui apakah terdapat hubungan tingkat pengetahuan terhadap kepatuhan lansia dalam menerapkan protokol kesehatan COVID-19 di Puskesmas Pangkalan Cirebon.
Metode: Penelitian observasional menggunakan desain Cross sectional dengan Uji non parametric, korelasi spearman. Sampel penelitian ini adalah Lansia sebanyak 88 responden di wilayah kerja Puskesmas Pangkalan Cirebon pada bulan juli 2022 dengan pengambilan data primer menggunakan kuesioner, teknik sampling menggunakan Non Probability Sampling secara Purposive Sampling.
Hasil: Analisis hubungan didapatkan bahwa p value sebesar (p<0,001) yaitu 0,000 dan nilai r didapatkan 0,671 menyatakan terdapat hubungan yang kuat,dan arah pengaruh variabel bebas terhadap variabel terikat adalah positif. Didapatkan mayoritas responden memiliki tingkat pengetahuan yang baik yaitu sebanyak (53,4%) dan kepatuhan lansia sebanyak (80,7%).
Kesimpulan: terdapat hubungan yang signifikan antara tingkat pengetahuan terhadap kepatuhan lansia dalam menerapkan protokol kesehatan COVID-19.
Kata Kunci: COVID-19, tingkat pengetahuan, kepatuhan lansia

Background: COVID-19 is a pandemic that has resulted in high mortality rates in various parts of the world. Knowledge about the COVID-19 pandemic is important to be known by all circles of society, especially in the elderly group (elderly. It is important for the elderly to have knowledge and compliance with COVID-19 and maintain health protocols, namely wearing masks, washing hands, and maintaining distance and abbreviated as 3M). .
Objective: to find out whether there is a relationship between the level of knowledge and the compliance of the elderly in implementing the COVID-19 health protocol at the Pangkalan Cirebon Health Center.
Methods: Observational research using cross sectional design with non parametric test, Spearman correlation. The sample of this study was the elderly as many as 88 respondents in the working area of the Pangkalan Cirebon Health Center in July 2022 with primary data collection using a questionnaire, the sampling technique using Non Probability Sampling by Purposive Sampling.
Results: Analysis of the relationship found that the p value of (p<0.001) is 0.000 which indicates the direction of the influence of the independent variable on the dependent variable is positive. It was found that the majority of respondents had a good level of knowledge (53.4%) and elderly compliance (80.7%).
Conclusion: there is a significant relationship between the level of knowledge on the compliance of the elderly in implementing the COVID-19 health protocol.
Keywords: COVID-19, level of knowledge, elderly compliance