Along with the increasing demand for building materials and the high cost of cement, innovation in the use of environmentally friendly and economical alternative materials is essential. Glass powder waste, which is difficult to decompose and potentially pollutes the environment, has potential as a cement substitute due to its favorable physical and chemical properties. Additionally, pumice, as a lightweight aggregate, can reduce the structure’s dead load and improve construction efficiency. This study aims to analyze the effect of adding glass powder waste as a cement substitute and using pumice aggregate on the compressive strength of lightweight concrete. Glass waste sourced from industrial and household origins was used as a partial replacement for cement, while pumice served as a substitute for coarse aggregate. The study employed an experimental method, with laboratory testing focused on compressive strength measurements. The results showed that the addition of glass powder at a certain percentage resulted in higher compressive strength compared to concrete without glass powder This suggests that the combination of glass powder and pumice stone can significantly increase the compressive strength of light concrete, although the efficiency of the mixture decreases at higher percentages. This research offers a practical alternative for utilizing local waste and natural aggregates in the development of concrete that is both environmentally sustainable and economically efficient.